较高的HbA1c-血红蛋白比率与内血管血栓切除术患者的不良结果有关
Feng Gao1, Shuaiyu Chen2, Xingjing Guo3
1Department of Radiology, Nanjing Jiangning Hospital, Nanjing Medical University, Nanjing, Jiangsu, China, njmu.edu.cn.
Behavioural neurology
|March 14, 2026
概括
HbA1c与血红蛋白比率 (HHR) 预测在内血管血栓切除术后缺血性中风患者的神经恢复不佳. 较高的HHR水平表明预后较差,有助于临床评估.
科学领域:
- 神经学 神经学
- 血管内治疗疗法 血管内疗法
- 生物标志物 生物标志物
背景情况:
- HbA1c与血红蛋白比率 (HHR) 与死亡率有关.
- 它在内血管血栓切除术患者的预后价值尚不清楚.
研究的目的:
- 评估HHR作为90天神经功能预后标志物.
- 在接受内血管血栓切除术 (EVT) 的患者中评估HHR.
主要方法:
- 353名EVT患者的回顾性研究 (2022年4月至2024年6月).
- 从HbA1c和血红蛋白水平计算的HHR.
- 多变量逻辑回归分析了HHR和功能结果 (修改的兰金尺度3-6在90天).
主要成果:
- 181名 (51.3%) 患者的90天治疗结果不佳.
- 更高的入院HHR独立地预测了更糟糕的功能恢复 (aOR:10.484,p=0.001).
- 在HHR和负预后之间存在非线性,剂量依赖的关系 (p=0.001). ROC 曲线值为 0.760.0 的值.
结论:
- 在EVT后的缺血性中风患者中,HHR升高与90天恢复较差相关.
- HHR显示出作为一个有价值的临床预后指标的潜力.
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