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集成的多组学阐明了微生物-代谢物相互作用,控制了豆酸液中的抗氧化能力
Wei Chen1,2,3, Lin Zhang4, Weikai Zhang1,2,3
1Luoyang Key Laboratory of POCT DiagnosticTechnology, Luoyang Polytechnic, Luoyang, China.
Journal of the science of food and agriculture
|March 14, 2026
概括
豆酸液 (MBSL) 发酵涉及特定的乳酸菌种,它们产生关键的抗氧化化合物. 这项研究揭示了驱动MBSLL的微生物和代谢动态.
科学领域:
- 食品科学 食品科学 食品科学
- 微生物学 微生物学
- 代谢学 代谢学 代谢学
背景情况:
- 豆酸液 (MBSL) 是一种传统的发酵食品.
- MBSL抗氧化能力的微生物和代谢基础在很大程度上仍未被探索.
- 了解这些因素对于利用其健康益处至关重要.
研究的目的:
- 阐明发酵期间MBSL中抗氧化能力发展的微生物和代谢基础.
- 识别关键的抗氧化生物标志物及其时间形成.
- 为了将微生物活动与代谢变化和功能结果相关联.
主要方法:
- 采用了综合的元基因组学和代谢学方法.
- 在发酵时间内分析了微生物种群和代谢物概况的动态变化.
- 使用了相关性网络和基因和基因组京都百科全书 (KEGG) 途径分析.
主要成果:
- 中期发酵阶段 (6-12小时) 对于抗氧化生物标志物积累至关重要,包括酸,表甲基素和甲基素.
- 抗氧化活性 (DPPH/ABTS) 显著增加,与特定的乳酸菌种相关 (例如,乳酸菌曲,乳酸菌 mudanjiangensis).
- 观察到代谢重编程,从氨基酸/脂质代谢转向中央碳代谢下调,与碳水化合物活性酶 (CAZy) 相关.
结论:
- 这项研究解读了微生物驱动的代谢重塑,负责MBSL的抗氧化能力.
- 关键代谢物积累和增强的功能性质之间存在明显的时间联系.
- 为优化MBSL作为促进健康的功能饮料提供了科学基础.
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