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Updated: Mar 16, 2026

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在5-HT7受体信号通路中,β-阿雷斯介导的Src激活的时空动态

Hyunbin Kim1,2, Yong Woo Lee3, Huimin Lee1,4,5

  • 1Department of Pharmacology, Seoul National University College of Medicine, Seoul, Republic of Korea.

The FEBS journal
|March 14, 2026
PubMed
概括

对于5-基三胺受体7 (5-HT7R) 的偏差配体,在自闭症谱系障碍模型中表现出差异性影响. 一个G蛋白偏差的配体诱导了类似ASD的行为,而一个β-arrestin偏差的配体激活了Src. kinase.

关键词:
5‐HT7 5‐HT7 的时间.使用GPCR偏差的信号传输.血清胺 (serotonin) 是一种神经元.这就是SRC src.这是一种β-arrestin.

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