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Updated: Mar 16, 2026

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过度的ER-线粒体合:一种DRP1驱动的机制,它是线粒体功能障碍和自功能受损的基础,在小鼠的压力诱导的抑郁症类行为中

Jia-Rui Zhang1, Jia-Yan Zhang1, Qing-Ya Sun1

  • 1School of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.

Redox biology
|March 14, 2026
PubMed
概括

Drp1的激活会破坏线粒体内质网膜接触部位 (MERCs),导致线粒体功能障碍和类似抑郁症的行为. 针对MERCs和mitophagy提供了潜在的抑郁症治疗策略.

关键词:
抑郁症 抑郁症 抑郁症线粒体内质网膜接触点 (MERCs) 是指线粒体内质网膜接触点.线粒体中的线粒体.线粒细胞衰变 (mitophagy) 是一种细胞衰变的过程.DRP1 是一个DRP1

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