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在odontohypophosphatasia中,NEFL与odontoblastic过程的抑制有关

Akira Nozoe1, Yasuhisa Ohata2, Makoto Fujiwara2

  • 1Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan.

Journal of bone and mineral metabolism
|March 14, 2026
PubMed
概括

低酸盐症 (HPP) 损害了质细胞 (OD) 的分化. 在Odonto-HPP细胞中神经纤维光链 (NEFL) 的过度表达破坏了OD形态学,这表明它在疾病病理生理学中发挥了作用.

关键词:
诱导多能干细胞 (iPS) 是一种诱导多能干细胞.体细胞质细胞.奥多多海波酸酶 (odontohypophosphatasia) 是一种存在于体内的生物.骨质母细胞的骨质细胞.

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