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确定关键的移植对受体重量比值,以确保完全右/完全左分割肝移植的安全:一个多中心的队列研究

Mingzheng Chen¹, Sui Shen¹, Zixuan Feng²

¹Department of Hepatobiliary and Pancreatic Surgery, Key Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Shulan (Hangzhou) Hospital, Shulan International Medical College, Zhejiang Shuren University, Hangzhou, China; School of Clinical Medicine, Hangzhou Normal University, Hangzhou, China.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

|March 14, 2026

概括

分析了分裂肝移植的结果. 移植对受体重量比 (GRWR) 超过1.15与更好的生存相关. 较低的GRWR可能适用于低风险患者,需要进一步研究.

科学领域:

肝病学肝病学是一种肝病学.
移植手术移植手术
器官捐赠器官捐赠器官捐赠器官捐赠器官捐赠器官捐赠器官捐赠器官捐赠器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器官捐献器

背景情况:

分裂肝移植对于解决器官短缺至关重要.
完全右/完全左分割肝移植 (FR/FLSLT) 的结果需要从多中心数据中验证.

研究的目的:

评估FR/FLSLT的结果.
确定影响FR/FLSLT接受者的生存时间的风险因素.

主要方法:

一项回顾性多中心研究,涉及中国五个中心的132名FR/FLSLT接受者.
风险因素的分析按移植对受体重量比率 (GRWR) 分层分层.

主要成果:

总体而言,接受者和移植的3年生存率分别为84.1%和81.8%.
GRWR > 1.15显示出明显更好的生存率比GRWR ≤ 1.15 (91.7%对比58.1%的接受者生存率).
接受者年龄>52和MELD得分>15是独立的死亡风险因素. 在高风险患者中,低GRWR移植增加了死亡风险.

结论:

具有GRWR> 1.15的FR/FLSLT与有利的结果有关.
在等待进一步验证之前,在没有风险因素的接受者 (年龄 ≤ 52,MELD ≤ 15) 中,可以考虑使用GRWR ≤ 1.15的移植.

关键词:

GRWRR 是一个很大的问题.结果结果结果结果.风险因素的风险因素是什么切割肝移植移植切割肝移植

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