强化骨的运动干预对儿童癌症幸存者的骨健康的影响:随机对照试验
Andres Marmol-Perez1, Esther Ubago-Guisado2, Jose J Gil-Cosano3
1Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Granada 18011, Spain; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Archives of physical medicine and rehabilitation
|March 14, 2026
概括
这项研究发现,一个为期9个月的在线骨强化炼计划并没有改善儿科癌症幸存者的部骨密度. 然而,它确实显示了部整体骨矿物质含量的改善.
科学领域:
- 儿科瘤学 儿科瘤学
- 骨健康研究 骨健康研究
- 运动科学运动科学
背景情况:
- 儿童癌症幸存者经常面临长期健康问题,包括骨健康受损.
- 强化骨的运动对于改善骨矿物质密度 (BMD) 在这个人群中至关重要.
- 在线干预提供了一种可行的方法,为在家的个人提供炼计划.
研究的目的:
- 为了评估9个月的在线强化骨的运动干预措施的有效性.
- 评估部部骨密度 (aBMD) Z-score和其他骨健康参数的变化.
- 确定对儿童癌症幸存者的骨矿物质含量 (BMC) 和aBMD的影响.
主要方法:
- 评估者盲目的随机对照试验,包括116名儿科癌症幸存者 (年龄在6-18岁).
- 干预组在家中进行了为期9个月的视频录制的骨强化炼计划 (俯卧,跳跃).
- 双能X射线吸收计 (DXA) 在基线和9个月测量了aBMD和BMC.
主要成果:
- 在干预后的两组之间,股骨部aBMD Z-score没有显著差异.
- 在全部aBMD Z-score (P=0.054) 中观察到边缘显著改善.
- 在干预组中,总关节BMCZ-score (P=0.039) 的显著改善.
结论:
- 在线强化骨的运动干预措施并没有在年轻的癌症幸存者中提高腿部部aBMD Z-score.
- 该计划导致整体关节骨矿物质含量 (BMC) Z-score 的改善.
- 在这种人群中,在家进行在线炼可能会为特定的骨健康参数带来好处.
相关概念视频
Bone Disorders
5.9K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.9K
Bone Remodeling
40.9K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
40.9K
Essential Minerals for Bone Health
7.0K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
7.0K
Bone Remodeling and Repair
7.5K
7.5K
Role of Vitamins in Maintaining Bone Health
5.9K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
5.9K
Fractures: Bone Repair
6.4K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
6.4K


