结核病和酒精使用;来自印度一个地方性结核病流行调查的结果
Giridharan Prathiksha1, Ariarathinam Newtonraj1, Kannan Thiruvengadam1
1ICMR- National Institute for Research in Tuberculosis, Chennai, India.
The Indian journal of tuberculosis
|March 14, 2026
概括
饮酒显著增加了结核病 (TB) 的风险. 这项研究发现,酒精消费与微生物学确认的肺结核 (MCPTB) 患病率高出四倍,特别是在老年,营养不良的人群中.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 基于人口的调查对于了解结核病 (TB) 与饮酒相关的流行病学至关重要.
- 酒精使用是结核病的潜在危险因素,需要进一步调查其对疾病患病率的影响.
研究的目的:
- 为了确定酒精使用与微生物学证实肺结核病 (MCPTB) 的患病率之间的关联,在印度进行了一项基于人口的大规模调查.
- 在消费酒精的人群中确定与MCPTB相关的因素.
主要方法:
- 在印度进行了一项全州跨部门调查,从180个集群中选了130,932名参与者.
- 查包括X射线和唾液检查,以诊断微生物学确认的肺结核病 (MCPTB).
主要成果:
- 酒精使用者中MCPTB的患病率为0.6%,非酒精使用者为0.12%,酒精使用者的调整后患病率 (aPR) 为4.2.
- 酒精使用者的MCPTB与年龄的增加 (aPR高达7.77),营养不良 (aPR高达14.0),以及过去的结核病史 (aPR 3.76) 有显著的关联.
- 诊断一个MCPTB病例所需的查人数在一般人群中为537人,在酒精使用组中为168人.
结论:
- 酒精消费与MCPTB的患病率与非酒精人士相比高出四倍.
- 年龄,营养不良和先前的结核病史是使用酒精的人群中MCPTB的重要风险因素.
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