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Updated: Mar 16, 2026

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AcrIIA7劫持了tracrRNA以阻止CRISPR-Cas系统的使用

So Yeon Lee1,2, Hyun Ho Park3,4

  • 1College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.

Nature communications
|March 15, 2026
PubMed
概括

一种新型的抗CRISPR蛋白,AcrIIA7,通过与tracrRNA结合来抑制CRISPR-Cas9,从而阻止了必需的核核蛋白复合体的形成. 这一发现揭示了一种新的RNA向机制,用于阻止CRISPR免疫力.

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