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全胰腺切除术后12个月营养不良和糖尿病结果:描述性队列研究
Ibrahima Maiga1, Antoine Vilotitch2, Béatrice Genoux1
1Department of Endocrinology, Diabetology and Nutrition, Grenoble Alpes University Hospital, University Grenoble Alpes, Grenoble, France.
在全胰腺切除术后,营养不良很常见,长期持续,体重显著下降. 虽然糖尿病是可以控制的,但对接受这种手术的患者来说,营养支持至关重要.
科学领域:
- 胃肠病学和肝病学
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
背景情况:
- 全胰腺切除术是一种罕见的手术,会导致终身内分泌和外分泌胰腺衰竭.
- 关于全胰腺切除术后的长期营养结果的数据有限.
- 这项研究解决了了解手术后营养状况和糖尿病控制的需要.
研究的目的:
- 在全胰腺切除术后的3个月和12个月评估营养不良的发生率.
- 为了评估手术后12个月3c型糖尿病的控制.
- 识别营养方面的挑战,并为术后护理策略提供信息.
主要方法:
- 一项描述性队列研究包括41名接受全胰腺切除术的成年患者.
- 营养状况被评估使用国家标准 (减肥,BMI,肌肉质量) 手术前,并在3个月和12个月.
- 糖尿病控制通过HbA1c和低血糖时间范围来评估.
主要成果:
- 营养不良的患病率从手术前的25%增加到3个月后的59.5%,12个月后的59.0%.
- 超过一半的患者在手术后12个月内体重减轻>10%.
- 所有患者都患上3c型糖尿病,HbA1c的中位数为8.0%,低血糖期的时间最小.
结论:
- 营养不良非常普遍,在全胰腺切除术后的12个月内持续存在,与显著的体重减轻有关.
- 在全胰腺切除术后的3c型糖尿病似乎是可以控制的.
- 对这种患者群体来说,系统的营养监测和优化的术后策略是必不可少的.
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