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Updated: Mar 17, 2026

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Published on: September 20, 2018

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通过染色体重塑器Chd1进行突触恒常的时间和细胞特异性调节

Danielle T Morency1,2, Tao Cui1, Yimei Cai1

  • 1Department of Pharmacology & Physiology, Georgetown University Medical Center, Washington, D.C., USA.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|March 15, 2026
PubMed
概括

染色体重塑剂Chd1通过调节特定细胞类型的突触可塑性,对稳定大脑电路功能至关重要. 它在自闭症谱系障碍 (ASD) 模型中的破坏导致运动缺陷和发作.

关键词:
在 Chd1 中使用.自闭症自闭症是什么表观遗传调节 表观遗传调节是一种.格利亚 (Glia) 是一个.神经肌肉结节是一个神经肌肉结节.预突触的恒常性塑性 预突触的恒常性塑性

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