[对于儿科败血症预后的三个评分系统的预测值:接收器操作员特征曲线和决策曲线分析]
Yongtian Luo1, Zhigui Jiang2, Zhen Yang1
1Department of Pediatric Intensive Care Unit, Affiliated Hospital of Guizhou Medical University, Guiyang 550000, China.
Zhonghua wei zhong bing ji jiu yi xue
|March 15, 2026
概括
座败血症评分 (PSS) 和儿科物流器官功能障碍-2 (PELOD-2) 有效地预测了儿科败血症的结果. 在没有冲击的情况下,PSS在败血症中表现出色,而PELOD-2在败血症冲击预后方面表现最好.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 败血症和败血症休克管理管理
- 临床评分系统的评估和评估.
背景情况:
- 败血症是儿童的危及生命的疾病,需要准确的严重程度评估.
- 现有的评分系统如pSOFA和PELOD-2在儿科败血症方面存在局限性.
- 座败血症评分 (PSS) 是一种用于评估败血症严重性的新工具.
研究的目的:
- 为了评估PSS,PSOFA和PELOD-2在儿科败血症中的诊断和预后价值.
- 为了比较这些得分的死亡率和疾病进展的预测准确性.
- 评估这些评分系统在指导紧急干预中的临床实用性.
主要方法:
- 在PICU中对226名儿科败血症患者进行了回顾性观察研究.
- 使用入院后24小时内数据计算PSS,pSOFA和PELOD-2分数.
- 使用ROC曲线进行预测准确度和决策曲线分析以获得临床实用性的分析.
主要成果:
- 没有幸存者的PSS,PSOFA和PELOD-2得分显著更高,感染败血症和机械通风率更高.
- 在没有冲击的情况下,PSS和PELOD-2在预测败血症死亡风险方面表现出高准确性 (AUC>0.9).
- PELOD-2显示出在败血症休克中死亡率的最高预测值 (AUC 0.947),而PSS在从败血症进展到败血症休克的最佳预测值 (AUC 0.799).
结论:
- PSS和PELOD-2对于预测儿科败血症没有冲击的不良结果是有价值的,PSS表现最好.
- PSS,pSOFA和PELOD-2都是用于预测败血症休克的不良预后的,PELOD-2显示出最高的性能.
- 这些评分对从败血症到败血症休克的进展的预测值是中等的.
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