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睡前小吃和亚临床甲状腺功能低下症之间的关联

Yuji Shimizu1,2, Nagisa Sasaki2, Asuka Oyama2

  • 1Department of General Medicine, Nagasaki University Graduate School of Biomedical Sciences.

Environmental health and preventive medicine
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概括

睡前小吃与亚临床甲状腺功能低下症 (SCH) 有关,可能是通过增加对内皮细胞修复的需求. 这种习惯可能表明早期的甲状腺和内皮功能障碍.

关键词:
在睡前吃零食.内皮细胞的修复.乙甲状腺体的人口.亚临床的甲状腺功能低下症.

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科学领域:

  • 内分泌学 在内分泌学.
  • 腎臟病學 (nephrology) 是一種醫學專業.
  • 心血管科学 心血管科学

背景情况:

  • 甲状腺激素对于内皮修复至关重要.
  • 睡前吃零食与慢性病 (CKD) 的风险增加有关.
  • 内皮功能障碍是CKD的一个关键特征,表明零食,内皮健康和甲状腺功能之间存在联系.

研究的目的:

  • 调查睡前小吃和亚临床甲状腺功能低下症 (SCH) 之间的联系.

主要方法:

  • 对1478名年龄在40-69岁的日本成年人进行了横截面研究,他们的甲状腺功能正常.
  • SCH被定义为提升的TSH (>4.01μIU/mL).
  • 通过自我报告评估的睡前小吃 (睡前2小时内每周≥3次).

主要成果:

  • 263名参与者报告说睡前小吃;81人有SCH.
  • 睡前小吃与SCH (OR 1.77;95% CI 1.05-2.99) 有意义地相关.
  • 在调整了包括饮食,代谢和心血管风险因素在内的混因素后,这种关联仍然显著.

结论:

  • 睡前吃零食与SCH.积极相关.
  • 这种联系可能源于对内皮细胞修复的生理需求增加.
  • 研究结果表明,睡前小吃可能是内皮和甲状腺功能障碍的早期标志物.