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Updated: Mar 17, 2026

Investigation of Macrophage Polarization Using Bone Marrow Derived Macrophages
10:07

Investigation of Macrophage Polarization Using Bone Marrow Derived Macrophages

Published on: June 23, 2013

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格利梅皮里德通过PPARγ介导的抑制机制调节LPS诱导的M1巨分极化

Wenkai Wang1, Hongrui Liu1, Pishan Yang1

  • 1Department of Periodontology, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, No. 44-1 Wenhua Road West, Jinan 250012, Shandong, China.

Biological & pharmaceutical bulletin
|March 15, 2026
PubMed
概括

格利梅皮里德有效地抑制M1巨细胞极化,并通过向PPARγ通路并抑制IκB-p65信号传递来减少炎症. 这揭示了glimepiride的新型抗炎机制.

关键词:
甲基化物 甲基化物这是一种炎症性炎症.巨细胞是一个巨细胞.巨细胞的两极分化过氧体增殖器激活的受体玛受体

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Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis07:45

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