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Eunsin Lee¹, Austin M Faught¹, Hyeri A Lee¹

¹Department of Radiation Oncology, The Ohio State University, Columbus, Ohio, USA.

Journal of applied clinical medical physics

|March 15, 2026

概括

世界上第一个多室Varian ProBeam 360°质子笔束扫描系统已成功投入临床使用. 严格的验证证实了精确的光束传递和剂量测量,以确保安全的患者治疗.

科学领域:

医学物理医学物理
辐射瘤学辐射瘤学
微粒疗法是一种微粒疗法.

背景情况:

质子疗法为癌症治疗提供精确的剂量递送.
质子疗法系统的进步对于改善临床结果至关重要.
瓦里安ProBeam 360°系统代表了质子疗法的重大技术进步.

研究的目的:

详细介绍第一个多室Varian ProBeam 360°质子笔束扫描系统的临床调试情况.
为了验证这一新型质子疗法技术的性能和准确性.

主要方法:

调试涉及整个能量频谱的光束特性 (范围,点尺寸,输出) 的特征.
测量了剂量参数,以在RayStation治疗计划系统 (TPS) 中开发剂量计算模型.
验证包括测试分布式布拉格峰值 (SOBPs) 和模拟患者计划,以及室间光束匹配.

主要成果:

质子束范围 (R80) 在门架室之间在0.4 ± 0.2毫米范围内一致.
在空中斑点大小和输出分别在5.7 ± 1.8%和1.0 ± 0.5%的范围内匹配.
TPS验证显示了与测量结果的高度一致,超过90%的数据通过了马标准 (2mm/2%为平面,3mm/3%为患者计划).

结论:

瓦里安ProBeam 360°系统的双门架室已成功投入临床运行.
综合测量和验证证实了该系统对安全有效的患者治疗的准确性.
这个调试里程碑为先进的质子疗法提供铺平了道路.

关键词:

在PBS调试中,PBS调试.在ProBeam 360°中使用.质子质子质子

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