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Updated: Mar 17, 2026

Dynamic Clamp Methods to Investigate Impaired Neuronal Excitability Associated with Autism
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Published on: October 17, 2025

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线粒体功能障碍和线粒体展开蛋白响应 (UPR):揭示它们在自闭症谱系障碍病原体中的作用

Merlin Jeejo1, Mrudula Mathew1, Kochupurackal P Mohanakumar1

  • 1Inter University Centre for Biomedical Research & Super Speciality Hospital (IUCBR & SSH), Mahathma Gandhi University Campus at Thalappady, Rubber Board PO, Kottayam, Kerala PIN 686009, India.

Mitochondrion
|March 15, 2026
PubMed
概括

线粒体功能障碍和氧化压力与自闭症谱系障碍 (ASD) 有关. 本综述探讨了线粒体未折叠蛋白反应 (UPRmt) 作为ASD病理生理学和潜在治疗点的关键因素.

关键词:
自闭症谱系障碍 自闭症谱系障碍肠-大脑轴 肠-大脑轴线粒体功能障碍 线粒体功能障碍线粒体展开的蛋白质反应反应这是一种米托金 (Mitokine) 基因.

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