通过TALE/NF-Y/Sp2转录因子对DECA-CCAAT复合元的合作阅读

Andrea Bernardini1, Nerina Gnesutta1, Roberto Mantovani1

  • 1Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20143, Milano, Italy.

概括

这项研究揭示了转录因子在DECA-CCAAT元素上的合作的结构基础,这对基因调节至关重要. 这些发现阐明了Sp2如何弥合TALE和NF-Y复合体,为发育基因表达提供了洞察力.

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