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使用磁共振成像评估婴儿大脑结构和功能之间的关联和父母报告的生命前两年的负面情感:叙述性审查

Sanjana Ravi¹, M Catalina Camacho², Kathryn L Humphreys¹

¹Vanderbilt University, 230 Appleton Place, #552, Nashville, TN 37204.

Neuroscience and biobehavioral reviews

|March 16, 2026

概括

早期的大脑发育,包括杏仁体和轨道前皮层 (OFC) 的结构和连接性,与婴儿的负面情感 (NA) 有关. 了解这些关联可能会为以后精神疾病的途径提供照明.

科学领域:

神经科学是一个神经科学.
发展心理学发展心理学
精神病学是一个精神病学.

背景情况:

婴儿期的负面情感 (NA) 预测了以后的精神疾病.
婴儿期是大脑和情感发育的关键时期.
了解早期的大脑行为联系对于识别精神病理风险至关重要.

研究的目的:

审查婴儿大脑结构/功能 (MRI) 和父母报告的NA之间的关联.
综合有关早期负面情绪的神经发育相关的发现.

主要方法:

使用磁共振成像 (MRI) 对婴儿 (0-2岁) 的研究的叙述性综述.
研究了大脑结构 (体积,白质完整性) 和功能 (连接性, perfusion) 与NA之间的关联.
合成的母公司报告的NA数据.

主要成果:

杏仁体体积/白质完整性与NA负相关.
轨道前皮层 (OFC) 连接/ perfusion 与 NA 负相关; OFC 白质完整性与 NA 积极相关.
默认模式网络 (DMN) 的连接协会各不相同.
大多数效果大小小,由于样本大小小和方法异质性存在局限性.

结论:

早期的大脑结构和功能,特别是在杏仁体和OFC,显示与婴儿负面情感的关联.
研究结果表明,潜在的神经发育途径可能导致精神病理学.
未来的研究需要更大的数据集,标准化方法和纵向设计来确认这些联系.

关键词:

大脑形态测量婴儿时期的婴儿时期.负面影响力负面影响力.静止状态的功能连接.气质气质是一种气质.白质的完整性白质的完整性

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