单个受试者的大脑体积相似性网络的生物学有效性,测试-重新测试可靠性和行为相关性
Minchul Kim1, Yae Ji Kim2, Marvin M Chun3
1Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
NeuroImage
|March 16, 2026
概括
来自MRI的体积相似性网络 (VSN) 是可靠的,用于大脑指纹. 然而,这种结构性大脑网络并不能预测注意力的个体差异.
科学领域:
- 神经成像是一种神经成像.
- 大脑网络分析 脑网络分析
- 结构性核磁共振 (MRI) 是一种结构性核磁共振.
背景情况:
- 来自MRI的T1加权体积相似性网络 (VSN) 是临床上可访问的.
- VSN的有效性,可靠性和行为相关性尚未得到充分证实.
- 评估VSN的可复制性和实用性对于未来的研究和临床应用至关重要.
研究的目的:
- 评估VSNs的可复制性和实用性.
- 为了确定VSN是否反映了大脑细胞架构.
- 评估VSN的测试-重新测试可靠性和行为相关性.
主要方法:
- 分析了三组数据集 (N=354) 用重复的MRI扫描和注意力测量.
- 使用区域间形态相似度指标生成VSN.
- 利用连接体指纹来提高可靠性,并利用基于连接体的预测建模来提高效用.
主要成果:
- VSN与细胞架构网络具有显著的空间相似性 (rho=0.23-0.22,p<0.01).
- VSN 显示了高的测试-重新测试可靠性,具有高的识别准确性 (91-100%).
- 与功能连接组不同,VSNs无法可靠地预测注意力的个体差异 (r<0.1,p>0.3).
结论:
- 单个大脑指纹的VSN表现出生物有效性和高可靠性.
- VSNs不适合预测个人注意力差异.
- 这些发现支持VSN用于神经成像研究和需要可靠的大脑结构识别的临床应用.
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