抵抗训练在久坐不动的成年人中进行长度8周的干预,重塑肠道微生物组
Daniel Straub1,2, Till Englert1,2, Antonia Beller1
1Quantitative Biology Center (QBiC), University of Tübingen, Tübingen, Germany.
Sports medicine - open
|March 16, 2026
概括
抵抗训练显著改变肠道微生物群,特别是在表现出更大的力量增长的个体中. 这些微生物组的转变,特别是丰富的有益细菌,可能表明改善了健康结果.
科学领域:
- 微生物组研究的研究.
- 运动生理学 运动生理学
- 人类健康 人类健康 人类健康
背景情况:
- 肠道微生物组对于新陈代谢,免疫力和衰老至关重要.
- 耐力训练对微生物群产生积极影响,但耐力训练的影响不太清楚.
- 这项研究调查了抵抗训练对久坐不动的成年人肠道微生物组合的影响.
研究的目的:
- 为了确定结构化抵抗训练是否会导致肠道微生物组合和多样性的显著变化.
- 探索强度改善和肠道微生物组变化之间的关系.
- 为了确定受阻力训练影响的特定微生物种群.
主要方法:
- 150名久坐不动的成年人 (24-61岁) 接受了为期8周的监督阻力训练计划.
- 便样本被采集用于16S rRNA基因测序和代谢学.
- 记录了训练数据 (重量,重复,负载) 和力量改进.
主要成果:
- 所有参与者都没有观察到微生物多样性或组成的整体变化.
- 个体内微生物组的变化与强度的提高相关.
- 高响应者 (≥33%的强度增加) 显示出显著的β多样性转移和时间依赖的微生物变化,包括Faecalibacterium和Roseburia hominis的丰富.
结论:
- 阻力训练会引发显著的,依赖时间的肠道微生物组变化,特别是在实质性增强力量的个体中.
- 这些变化与耐力训练中观察到的变化相似.
- 观察到的变化表明,对整体健康有潜在的益处.
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