自闭症和神经典型女孩的不良童年经历
Jon Ebert1, Rachael A Muscatello1,2, Trey McGonigle3
1Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
概括
患有自闭症谱系障碍 (ASD) 的儿童比通常发育的同龄人有更多的不良童年经历 (ACE). 结合起来,ASD和ACE会增加女孩焦虑和抑郁的风险.
科学领域:
- 儿童心理学 儿童心理学
- 神经发育障碍 神经发育障碍
- 心理健康研究 心理健康研究
背景情况:
- 儿童不良经历 (ACE) 与长期的负面健康结果有关.
- 以前的研究表明,患有自闭症谱系障碍 (ASD) 的儿童可能有更高的ACE风险.
- 现有的研究是有限的,主要集中在男性人群.
研究的目的:
- 研究女性儿童的ACE,比较ASD和典型发育 (TD) 同龄人.
- 检查诊断状态,年龄和青春期对ACE的影响.
- 评估ASD,焦虑和抑郁症状在女孩和没有ASD之间的关系.
主要方法:
- 研究包括212名6至12岁的女性儿童 (112名患有自闭症,100名TD).
- 进行了诊断评估和10项ACE问卷.
- 统计分析包括威尔科克森等级和试验,负二项式模型,线性回归和斯皮尔曼相关性.
主要成果:
- 自闭症女孩报告的ACE明显高于TD女孩 (p=0.024).
- 患有自闭症的女孩患有抑郁和焦虑症状更高,与ACE总和正相关.
- 在诊断,年龄和青春期之间没有发现显著的相互作用.
结论:
- 自闭症谱系障碍和ACE可能会协同增加女孩患精神疾病的风险.
- 早期识别和针对自闭症青少年ACE的有针对性的干预措施至关重要.
- 对自闭症不良事件的量身定制治疗的进一步研究是有必要的,以防止负面的健康后果.
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