[对5 573名3至18岁儿童的不同骨龄评估方法进行比较]
1Department of Growth and Development, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Beijing 100020, China.
Zhonghua er ke za zhi = Chinese journal of pediatrics
|March 16, 2026
概括
坦纳-怀特豪斯3 (TW3) 和CHN骨年龄 (BA) 标准显示,与时间学年龄 (CA) 有显著的偏差,特别是在青春期的儿童中. 中国05标准的偏差较小,但世俗的增长趋势影响了身高评估.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 放射学 放射学是一门学科.
- 人类测量学 人类测量学.
背景情况:
- 准确的骨龄 (BA) 评估对于评估生长障碍至关重要.
- 现有的标准,如坦纳-怀特豪斯3 (TW3),中国05和CHN有不同的应用.
- 世俗增长趋势对中国儿童的BA评估的影响需要研究.
研究的目的:
- 为了比较TW3,China05和CHN骨架成熟度标准之间的实际应用差异,用于BA评估.
- 评估这些BA标准与中国儿童的时间年龄 (CA) 的一致性和偏差.
- 分析世俗增长趋势对相当的骨成熟度水平的身高估计的影响.
主要方法:
- 在北京,对6013名3-18岁儿童进行了横截面研究.
- 使用TW3 (RUS和手掌得分),中国05 (RUS和手掌得分) 和CHN方法计算BA.
- 统计分析包括威尔科克森签名等级测试,麦克纳马-博克测试和弗莱斯·卡帕系数用于比较和一致性评估.
主要成果:
- TW3和CHN BA显示了与CA的显著偏差,特别是在青春期儿童中.
- 中国05 BA与CA的偏差相对较小,但在相当的骨成熟度得分上的高度不同.
- 总体而言,Fleiss Kappa系数表明TW3 RUS (0.54男孩,0.51女孩) 和China 05 RUS (0.54男孩,0.51女孩) 的适度一致性,手掌方法的值较低.
- 研究中的儿童通常比参考人群更高,具有相同的骨成熟度得分 (SMS).
结论:
- 由于与CA的显著偏差,TW3和CHN BA标准需要仔细解释.
- 中国05标准虽然更接近CA,但需要考虑长期增长趋势,以准确评估增长潜力.
- 综合的BA解释应该整合多维指标和动态增长趋势,以基于证据的临床决策增长障碍.
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