牙损失对死亡率的高维效应异质性
Y Matsuyama1, S Kiuchi1, T Yamamoto2
1Department of Dental Public Health, Graduate School of Medical and Dental Sciences, Institute of Science, Tokyo, Japan.
Journal of dental research
|March 16, 2026
概括
失去牙增加了老年人的死亡风险. 这种风险在男性,健康状况不佳和社会经济地位较低的人群中更高,突出了脆弱的子组.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 对老年人来说,失去牙是一个重大问题,可能与死亡率的增加有关.
- 了解影响这种关联的因素对于有针对性的干预至关重要.
研究的目的:
- 为了检查牙脱落与日本老年人全因死亡率之间的异质性.
- 确定老年人的子组,牙损失对他们的死亡风险更大.
主要方法:
- 利用了来自2013年日本老年学评估研究的69,265名65岁以上的日本成年人的数据.
- 使用逆概率权重和因果森林机器学习来估计平均处理效应 (ATE) 和条件平均处理效应 (CATE).
- 分析了44个共变量,包括人口,经济,社会,健康和社区因素,以评估异质性.
主要成果:
- 牙损失 (<20颗天然牙) 与所有死因死亡风险增加3.2个百分点显著相关 (ATE = 0.032).
- 观察到统计学上显著的异质性,男性,健康状况不佳的个体和社会经济地位较低的个体中,与牙脱落相关的死亡风险更高.
- 心脏病,性和抑郁症被确定为这种异质性的关键贡献者.
结论:
- 失去牙是老年人死亡风险升高的重要指标.
- 这种风险的程度在不同的人口子组之间有很大差异,特别是影响弱势个体.
- 调查结果强调了将口腔健康作为综合老年护理和公共卫生战略的一部分的重要性.
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