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主要头痛的儿童和青少年的执行功能

Zahraa Nima^1,2, Amalie Berring-Uldum^1,2, Nanette Mol Debes^1,2

¹Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

Journal of child neurology

|March 16, 2026

概括

与健康对照组相比,患有主要头痛障碍的儿童和青少年表现出较差的执行功能,特别是在Trail Making Test上. 较高的头痛频率与偏头痛和混合头痛组的特定执行功能测试中的表现较差相关.

科学领域:

儿科神经学儿科神经学
神经心理学神经心理学
认知科学认知科学

背景情况:

头痛疾病,包括偏头痛,在儿童和青少年中普遍存在,并导致残疾.
认知障碍,特别是执行功能缺陷,可能与头痛有关,但研究有限.
识别执行职能问题对于及时提供支持和干预至关重要.

研究的目的:

为了研究和比较被诊断患有初级头痛障碍的儿童和青少年的执行功能与对照组.
探索儿童头痛患者头痛频率和执行功能表现之间的关系.

主要方法:

一项横截面病例控制研究,涉及109名患有主发性头痛的儿科患者和112名无头痛的对照患者.
执行功能使用Delis-Kaplan执行功能系统 (D-KEFS) 进行评估,包括Trail Making Test,图形设计测试和口头流利性测试.
统计学显著性是使用P值值<0.05.05来确定的.

主要成果:

与对照组相比,儿科头痛患者在Trail Making测试中表现明显差 (P=.015).
在偏头痛和紧张型头痛子组之间没有发现显著的执行功能差异.
头痛频率增加与口语流利性测试-切换 (偏头痛患者,P=.04) 和Trail Making测试-数字-字母切换 (混合头痛,P=.037) 的表现更差有关.

结论:

这项研究表明,初级头痛疾病与儿童和青少年执行功能受损之间存在潜在的关联.
在头痛组中观察到特定的执行功能缺陷,特别是在Trail Making Test上.
需要进一步的研究来确定因果关系,并了解将头痛与执行功能联系在一起的机制.

关键词:

青少年青少年青少年孩子们的孩子们的孩子们的孩子们.执行职能执行职能是指执行职能.偏头痛偏头痛偏头痛偏头痛紧张类型的头痛是紧张类型的头痛.

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