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Updated: Mar 17, 2026

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
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溶解中介pH在基本药物-科波维无形固体分散的释放行为中的作用

Taiga Uekusa1, Siddhi S Hate2, Kirk A VanDer Kamp2

  • 1Department of Industrial and Molecular Pharmaceutics, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States.

Molecular pharmaceutics
|March 16, 2026
PubMed
概括

具有高药物负载的无形固体分散 (ASD) 显示出由于富含药物的层而依赖于pH的释放. 较低的药物负载ASD表现出由聚合物控制的pH独立释放,影响药物的生物可用性.

关键词:
无形固体分散的分散.无形−无形阶段分离的分离.凝层的pH值 凝层 pH值释放机制的释放机制

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