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基于体外发酵和细胞模型,选促进矿物质吸收的益生菌

Bing Liu^1,2, Yuejian Mao³, Jing Yang³

¹The First Hospital of Shanxi Medical University, Taiyuan, China.

Frontiers in microbiology

|March 16, 2026

概括

像Bifidobacterium lactis Ca360这样的益生菌可以增强,铁和等必需矿物质的吸收. 这项研究选了多种益生菌菌株,以确定它们提高矿物质吸收的能力,并确定了相关的关键机制.

科学领域:

微生物学微生物学
营养科学营养科学
胃肠病学胃肠病学

背景情况:

矿物质缺乏是一个重大的全球健康挑战.
益生菌因其通过增强肠道吸收来调节营养的潜力而得到认可.

研究的目的:

系统地选乳酸菌和双菌菌株,以检查它们促进矿物质吸收的能力.
评估选定益生菌候选人的体外发酵代谢和矿物质吸收增强性质.
阐明益生菌改善矿物质生物可用性的机制.

主要方法:

在体外对多种益生菌菌株进行查,以检测发酵代谢和促进矿物质吸收的特性.
多参数选,选择八个有前途的菌株.
使用Caco-2细胞模型评估选定菌株的评估,以评估矿物质吸收能力 (,铁,).

主要成果:

在酸生产,短链脂肪酸 (SCFA) 生产和植物酶活性中观察到显著的菌株特异性变异.
在L.I.L.里面, 脚部 Fe-01 和 B. 脚部在Caco-2细胞中,Ca360表现出优异的植物酶活性和增强的,铁和吸收.
一个B. B. B. B. 乳酸Ca360在,铁和吸收方面显示出最显著的改善,可能是通过酸生产和植物酸盐水解.

结论:

比菲多细菌乳糖 (Bifidobacterium lactis) Ca360是一种高效的益生菌菌株,可增强,铁和的吸收.
益生菌介导的矿物质吸收是由包括酸生产和植物酸盐水解在内的机制促进的.
这项研究为开发有针对性的益生菌以改善矿物质生物可用性提供了基础.

关键词:

B. 乳糖 Ca360 360 年和是最重要的.在体外发酵发酵.铁是铁,铁是铁,铁是铁.矿物质的吸收矿物质的吸收.,和的使用情况.

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