对萨尔科佩尼亚指标对接受激进囊切除术的生存预测的分析
Enes Malik Akdaş1, Kerem Teke2, Engin Telli2
1Department of Urology, Kocaeli City Hospital, Kocaeli, Turkey.
Bladder cancer (Amsterdam, Netherlands)
|March 16, 2026
概括
放射性肉症指标预测激进囊切除术后膀癌患者的整体存活率. 具体的骨肌指数和psoas肌指数参数是男性的预后,而骨肌密度是女性的预后.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 老年病的医生 老年病的医生
背景情况:
- 萨科佩尼亚是癌症中新兴的基于成像的预后因素.
- 在经过激进囊切除术的膀癌患者中 Sarcopenia 的性别特异性放射性指标尚未确定.
研究的目的:
- 确定放射性肉类的参数,以预测进行激进囊切除术 (RC) 的患者的整体存活率 (OS).
主要方法:
- 对接受RC的183名膀癌患者的回顾性分析.
- 腹部CT扫描用于提取骨肌肉区域和L3.3的Hounsfield单位.
- 计算了五个肉症参数:SMI类型1,SMI类型2,PMI类型1,PMI类型2和SMD.
- 使用单变量和多变量考克斯回归分析研究了对OS的预后影响.
主要成果:
- 在男性中,单变量分析显示年龄,pT,pN,SMI类型1,SMI类型2和PMI类型2对OS具有重要意义.
- 在女性中,单变量分析显示PT,PN和SMD对OS具有重要意义.
- 多变量分析证实SMI类型1,SMI类型2和PMI类型2是男性OS的预后因素.
- 多变量分析证实SMD是女性OS的显著预后因素.
结论:
- 性别特定的放射性肉参数对接受RC的患者显著影响OS.
- SMI类型1,SMI类型2和PMI类型2是男性的预测因素.
- 对于接受RC的女性来说,SMD是一种预测器.
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