微生物队列:为共发生网络的模块化概念带来生态意义
Felix Milke1, Sarahi L Garcia1,2,3, Meinhard Simon1,3
1Institute for Chemistry and Biology of the Marine Environment (ICBM), School of Mathematics and Science, Carl von Ossietzky University Oldenburg, 26129 Oldenburg, Germany.
ISME communications
|March 16, 2026
概括
微生物群落形成稳定的子群体,称为队列. 这些队列无处不在,可预测,在各种环境中具有生态意义,揭示了基本的微生物组织.
科学领域:
- 微生物生态学 微生物生态学
- 生物信息学是一种生物信息学.
- 系统生物学 系统生物学
背景情况:
- 微生物群落表现出复杂的相互作用,难以直接观察.
- 同时发生的网络推断社区结构和潜在的生物相互作用.
- 模块化是微生物网络的共同特征,但其生态意义尚未得到充分探索.
研究的目的:
- 测试微生物共发生网络 (队列) 中的集群是否是普遍的和生态意义上的单位.
- 评估各种生态系统中微生物队列的无处不在,稳定性和环境特异性.
- 了解微生物社区组织中模块化的生态意义.
主要方法:
- 对25个已发表的16S rRNA基因扩增序列测序数据集 (14,160个样本) 的元分析.
- 推断微生物共发生网络及其模块化结构 (队列).
- 评估队列的无处不在,稳定性,环境特异性和对环境梯度的反应.
主要成果:
- 微生物共发生网络在各种生物群中始终表现出高度的模块化.
- 推断的队列无处不在,包括多达90%的社区组成.
- 在不同的环境中发现了类似的队列,对环境梯度表现出可预测的反应,独立于数据集大小或推断算法.
结论:
- 模块化是微生物社区组织的一个基本和可概括的特征,表明稳定的子社区 (队列).
- 微生物队列代表有意义的组织水平,具有决定性和可预测的组成.
- 这些发现完善了微生物生态,培养策略和微生物动态的预测建模.
相关概念视频
Gene Regulation in Microbial Communities: Quorum Sensing
844
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
844
Microbial Morphologies
4.7K
Bacterial and archaeal cells exhibit remarkable diversity in shape and structure, critical in their adaptability and functionality. Among bacteria, the most commonly observed shapes include cocci and bacilli. Cocci are spherical and may exist singly or in groupings such as pairs (diplococci), chains (streptococci), clusters (staphylococci), or tetrads. Bacilli, in contrast, are rod-shaped and can also occur as single cells, in pairs, or chains, depending on their environmental and genetic...
4.7K
Microbial Classification System
1.5K
Classification is the process of organizing organisms into hierarchically inclusive groups based on their phenotypic similarities or evolutionary relationships. A species comprises one or more strains, and closely related species are grouped into genera. Genera are further classified into families, families into orders, orders into classes, and so forth, up to the domain level, which is the broadest taxonomic rank derived from a combination of phenotypic and genotypic data.The nomenclature of...
1.5K
Types of Microorganisms
3.3K
Microorganisms are a diverse group of microscopic entities broadly categorized into cellular and acellular types based on their structural organization. Cellular microorganisms include bacteria, archaea, fungi, protozoa, and algae, while acellular microorganisms are represented by viruses.Cellular MicroorganismsBacteriaBacteria, tiny prokaryotic organisms, exhibit fascinating shapes such as rods, spheres, and spirals. They adapt to diverse habitats, including soil, water, and human-associated...
3.3K
Environmental Applications of Microorganisms
1.4K
Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...
1.4K
Coordination of Gene Expression Processes in Bacteria
826
The DNA replication, transcription, and translation processes are intricately coupled in bacteria, allowing efficient gene expression and rapid protein synthesis. While this physical and functional coordination is advantageous, it introduces challenges that bacteria overcome through specific regulatory mechanisms.Coupling of Replication, Transcription, and TranslationThe coupling of replication, transcription, and translation is a hallmark of bacterial gene expression. As the replisome unwinds...
826


