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在恶性瘤中驱动蛋白质组不平衡会引起蛋白质组灾难,并赋予瘤抑制

Babul Moni Ram, Omprakash Shriwas, Meng Xu

    bioRxiv : the preprint server for biology
    |March 16, 2026
    PubMed
    概括

    热冲击因子1 (HSF1) 在癌细胞中保持蛋白质稳定性. 破坏HSF1会导致蛋白质灾难,导致瘤抑制,并提供一种新的癌症治疗策略.

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