1990-2021年子宫内膜异位症负担的全球趋势:使用GBD 2021数据和到2036年的预测进行社会人口统计分析
Fei Liu1,2, Suzhen Yuan1,2, Qing Yan1,2
1Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
International journal of women's health
|March 16, 2026
概括
在全球范围内,子宫内膜异位症的负担正在下降,但由于人口增长,总病例正在增加. 青少年是预防和控制战略的关键目标,以减少健康不平等.
科学领域:
- 流行病学 流行病学
- 全球健康 全球健康
- 妇女健康 妇女健康
背景情况:
- 子宫内膜异位症是一种慢性炎症性疾病,影响女性的健康,导致骨盆疼痛和不孕.
- 它对全球医疗保健系统造成了巨大的负担.
研究的目的:
- 从1990-2021年分析子宫内膜异位症的全球负担和趋势.
- 识别子宫内膜异位症流行和发病率的地理,社会经济和年龄相关差异.
- 预测未来的趋势,并为有针对性的预防和管理策略提供信息.
主要方法:
- 使用的全球疾病负担 (GBD) 2021年数据 (1990-2021年).
- 分析了年龄标准化流行率 (ASPR),年龄标准化发病率 (ASIR),估计年度百分比变化 (EAPC) 和根据残疾调整的寿命年数 (DALY).
- 采用了先进的分析,包括不平等指数 (SII,CIX),边界分析和贝叶斯年龄周期队列 (BAPC) 模型.
主要成果:
- 全球年龄标准化流行率和发病率下降 (分别为-1.02%和-1.00%EAPC).
- 由于人口增长和老龄化,总病例和DALY增加.
- 在社会人口指数 (SDI) 较低的地区观察到更高的负担;东亚,南亚和东南亚的比例最高.
- 青少年 (15-19岁) 患病率很高,这表明他们属于预防关键群体.
- 尽管绝对差异缩小,但中等和高SDI地区的相对健康不平等加剧.
结论:
- 虽然标准化子宫内膜异位症负担在全球范围内下降,但绝对负担在增长,地理和年龄差异持续存在.
- 到2036年的预测显示,标准化负担继续下降,但不平等仍然存在.
- 优先考虑青少年群体,并为高负担群体制定量身定制的战略,对于公平的全球性子宫内膜异位症减少至关重要.
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