阴茎的参与与脏盆腔状细胞癌相关:一个病例报告和机制性考虑
Kotaro Masaki1, Takuya Tsujino1, Hiroyuki Okada1
1Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Japan.
Frontiers in oncology
|March 16, 2026
概括
本报告详细介绍了第一个由骨的状细胞癌 (SCC) 引起的阴茎转移的记录病例. 先进的上泌尿道癌可以扩散到阴茎,通常通过静脉通路.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 盆地状细胞癌 (SCC) 是一种罕见的上部泌尿道恶性瘤.
- 从脏盆腔SCC引起的阴茎转移在医学文献中以前没有被记录.
研究的目的:
- 报告第一个从脏骨盆SCC引起的阴茎转移病例.
- 讨论这种罕见事件的诊断和潜在的转移途径.
主要方法:
- 一个74岁的男性患有阴茎结节的病例介绍.
- 利用磁共振成像 (MRI) 和对比增强计算机断层扫描 (CT) 进行诊断.
- 对脏盆腔和阴茎病变进行了组织病理学和免疫组织化学检查.
主要成果:
- 这位患者出现了阴茎结节和左侧大脏骨盆瘤,肝脏和状淋巴结转移.
- 组织病理学证实了SCC在两个位置上的质化,免疫组织化学支持泌尿器官起源.
- 没有观察到区域性淋巴腺病,这表明非淋巴转移的途径.
结论:
- 这一案例代表了第一个报告的阴茎参与的情况,这是脏骨盆SCC的次要原因.
- 在患有高级上泌尿道恶性瘤的患者中,阴茎病变应该引起对转移的怀疑.
- 在这种转移模式中,建议采用血源性逆向静脉传播途径.
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