对乳腺癌的低分离放射治疗的研究证据差距分析:一项文献识别知识图表研究
Bingyu Liu1, Junbao Xu1, Jianing Wang1
1School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China.
Frontiers in oncology
|March 16, 2026
概括
乳腺癌的低分离放射疗法 (HFRT) 显示了早期疾病的强有力的证据. 然而,需要更多关于复杂病例的长期安全性和患者结果的研究.
科学领域:
- 在瘤学瘤学.
- 辐射疗法 辐射疗法
- 医疗信息学 医疗信息学
背景情况:
- 低分离放射治疗 (HFRT) 是早期乳腺癌的标准治疗方法,得到了指导方针和试验的支持.
- 需要澄清HFRT研究,证据质量和临床指南的采用之间的协调.
研究的目的:
- 分析出版趋势,合作模式和乳腺癌HFRT研究热点.
- 评估临床证据的演变,并确定乳腺癌HFRT的研究缺口.
主要方法:
- 使用CiteSpace和VOSviewer对出版物的图书统计分析 (2014-2024年).
- 审查PubMed的临床试验,以评估证据的发展.
- 应用知识映射框架来识别研究缺口.
主要成果:
- 出版物增长遵循了三个阶段的模式:缓慢增长,快速扩张和稳定.
- 关键的研究领域转向毒性,剂量优化和以患者为中心的结果.
- 长期毒性数据,患者报告的结果,以及晚期疾病或后重建的证据存在显著差距.
结论:
- 高FRT研究正在成熟,支持其在早期乳腺癌中的使用.
- 进一步的研究对于长期的安全性,患者报告的结果和复杂的临床情景至关重要.
- 未来的研究应该专注于前性研究,高级分析和标准化报告.
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