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Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
甲状腺素作为最小侵入性手术期间压力的参数
Ervin Matovic1,2, Samir Delibegović1,2
1Clinic for Surgery, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina. (Drs. Matovic and Delibegović).
最少的侵入性手术 (镜胆囊切除术) 引起的荷尔蒙压力比开放式手术少. 在腹腔镜手术期间降低腹腔内压力进一步降低了身体的应激反应.
科学领域:
- 一般外科 整体外科
- 内分泌学 在内分泌学.
- 最少侵入性的手术
背景情况:
- 手术期间的荷尔蒙应激反应尚未完全理解.
- 甲状腺激素甲状腺激素 (T4) 可以作为手术压力的标记物.
研究的目的:
- 评估腹腔镜胆囊切除术 (LC) 与开放胆囊切除术 (OC) 期间的荷尔蒙应激反应,特别是T4水平.
- 为了比较标准 (12-15 mmHg) 与低 (6-8 mmHg) 的腹内压力在LC期间对荷尔蒙压力的影响.
主要方法:
- 一个队列观察性研究,涉及110名患者.
- 患者被分为OC (40名患者) 和LC (70名患者) 组.
- 脊髓癌患者进一步根据腹腔内压力 (标准与低) 分为子组.
- 甲状腺素 (T4) 水平作为压力指标被监测.
主要成果:
- 与LC相比,开放胆囊切除术 (OC) 导致术后T4水平显著提高.
- 与OC相比,LC的整体应激反应在LC中的强度较小.
- 使用低腹腔内压进行的LC显示应激反应低于使用标准压力.
结论:
- 最少侵入性手术 (LC) 与开放式手术 (OC) 相比,具有荷尔蒙方面的优势.
- 在LC期间利用低腹内压力进一步降低了与标准压力相比,身体的应激反应.
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