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在视网膜静脉封闭后的斑点水下进行平衡盐溶液的视网膜下注

Yue Pan¹, Xiang Zhang¹, Zetong Nie¹

¹Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.

Frontiers in medicine

|March 16, 2026

概括

视网膜下平衡盐溶液 (BSS) 注射与玻璃切除术相结合,对由于视网膜静脉封闭 (RVO-ME) 的耐火性黄斑胀 (Refractory macular edema) 显示了解剖上的好处. 这种方法可以减少复发,为抗VEGF治疗提供潜在的替代方案.

科学领域:

眼科医生眼科眼科
视网膜疾病视网膜疾病
手术创新在外科创新.

背景情况:

由于视网膜静脉封闭 (RVO-ME) 引起的黄斑是视力丧失的重要原因.
标准的抗血管内皮生长因子 (抗VEGF) 治疗可能在某些RVO-ME病例中不足.
对耐火性RVO-ME.需要新的治疗策略.

研究的目的:

为了评估RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.RVO-ME.
为了比较帕斯普拉纳玻璃切除术 (PPV) 结果与内BSS注射与持续的静脉内抗VEGF治疗.

主要方法:

追溯分析19个眼睛的RVO-ME耐火抗VEGF治疗.
一组接受了PPV与内部限制膜 (ILM) 剥离和底BSS注射.
对照组继续接受内抗VEGF注射.

主要成果:

两组之间最终最佳校正视敏度 (BCVA) 没有显著差异 (p=0.081).
手术组显示中央黄斑厚度显著减少 (p=0.048).
手术组的复发率较低 (40.0%vs88.9%,p=0.051) 和复发时间较长.

结论:

带有ILM剥离和上腺BSS注射的PPV是一种可行的方法,用于耐火RVO-ME.
该程序提供了显著的解剖学改善和控制的潜力.
需要进一步的前性试验来确认视觉结果和解剖效益.

关键词:

抗血管内皮生长因子的抗血管内皮生长因子这是一个平衡的盐溶液.斑点水斑点水是什么?帕斯·普拉纳视切除术 (Pars plana vitrectomy) 是一个切除术.视网膜静脉闭塞视网膜静脉闭塞在子肠内注射.

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