在上腔通道脱过程中自发自动插入的功能和放射性概况
Cassandre Djian1, Charlotte Hautefort1, Philippe Herman1,2
1Centre de Référence des Maladies Vestibulaires et Cochléo-vestibulaires Rares (VERTICO), Fondation Pour l'Audition, IHU reConnect, Université Paris Cité, Institut Pasteur, AP-HP, Hôpital Lariboisière.
概括
在上半圆通道脱声症 (SSCD) 中自发自动插入会导致类似于手术插入的通道功能障碍,但不会解决第三窗口症状. 这表明SSCD的适应不完全.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经科学是一个神经科学.
- 静脉管系统疾病 静脉管系统疾病
背景情况:
- 上半圆通道脱 (SSCD) 是一种在上半圆通道覆盖的骨头脱的情况.
- 由于"第三窗口"效应,SSCD可能导致听觉和前庭症状.
- 自发自插是SSCD患者中鲜为人知的现象.
研究的目的:
- 在SSCD中描述自发自动插入的特征.
- 为了比较自动插入的临床,放射学和电生理学特征与未经治疗和手术治疗的SSCD.
- 了解SSCD的病理生理学. 了解SSCD的病理生理学.
主要方法:
- 对59个SSCD耳朵进行了回顾性观察研究.
- 分类为未经处理 (n=36),自动插入 (n=5) 和手术插入 (n=18) 组.
- 评估包括临床评估,听力测量,视频头部脉冲测试 (vHIT),宫前庭引起的肌原潜力 (cVEMP) 和高分辨率MRI.
主要成果:
- 与未经治疗的SSCD相比,自动插入和手术插入组显著减少了vHIT增益 (P=0.0003).
- 自动听力在自动插入组 (80%) 中持续存在,但在手术后减少了 (22.2%,P<0.0001).
- 在未经治疗和自动堵塞的耳朵中,cVEMP的值很低,但在手术后显著上升 (P<0.001).
结论:
- 自发自插模仿了关于运河功能障碍的手术插.
- 自动插入并不能缓解第三窗口的症状,如自发声.
- 这种现象可能代表SSCD病理生理学的不完整,自发的适应.
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