相关实验视频

Updated: Mar 18, 2026

Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome

Published on: September 27, 2024

儿科长期COVID患者的微循环障碍和动脉硬性增加

Julie Boever¹, André Jakob², Clara Paetzold²

¹Department of Pediatric Cardiology and Pediatric Intensive Care, University Hospital, LMU Munich, Munich, Germany. Julie.Boever@med.uni-muenchen.de.

European journal of pediatrics

|March 17, 2026

概括

小儿长期COVID患者表现出显著的微血管损伤和动脉硬,表明血管变化有助于他们的症状. 这些发现凸显了长期COVID儿童心血管监测的必要性.

科学领域:

心血管研究研究心血管研究
儿科健康儿科健康
传染性疾病传染性疾病

背景情况:

微血管和内皮功能障碍与SARS-CoV-2相关的疾病有关.
成年长期COVID患者表现出毛细血管稀疏和内皮功能障碍,这表明血管机制是持续症状的原因.
儿科长期COVID与微血管损伤和动脉硬度增加有关.

研究的目的:

调查小儿长期COVID中微血管和内皮功能障碍的作用.
为了评估长期COVID儿童的微循环和动脉硬.
识别儿童长期COVID症状的潜在血管机制.

主要方法:

在儿童医院进行的比较队列研究.
语言下侧流暗场 (SDF) 成像用于分析微循环 (MFI,TVD,PPV).
周围动脉度计 (EndoPAT) 用于评估内皮功能和动脉硬度 (RHI,AIx@75).

主要成果:

小儿长期COVID患者 (n=37) 与健康对照组 (n=46) 相比,MFI,TVD和PPV显著减少.
微循环变化在呼吸障碍患者中最为明显.
血管变化是可测量的,包括微血管减少和动脉硬度增加.

结论:

可测量的血管变化,包括微血管减少和动脉硬度增加,在儿科长期COVID中存在.
这些发现支持血管变化在儿科长期COVID的发病过程中的作用.
心血管监测和随访对于治疗长期COVID的儿童至关重要.

关键词:

动脉的硬性动脉的硬性内皮质功能障碍内皮质功能障碍微循环是一种微循环.儿科长期COVID患者周围动脉度计 (PATM) 是一种外围动脉度计.侧流暗场成像侧流暗场成像

更多相关视频

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Published on: May 3, 2018

相关概念视频

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

COPD: Pathogenesis and Clinical Features

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

Peripheral Artery Disease I: Introduction

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...