通过Cap-ScoreTM评估的精子容量能力对ICSI成功的影响很小
G Charles Ostermeier1,2, Anna Lysenko-Brockman3, Haneen Taha3
1M Health Fairview, Minneapolis, United States.
Journal of assisted reproduction and genetics
|March 17, 2026
概括
通过Cap-Score测量精子容量能力较低的男性没有显著不同的细胞内精子注射 (ICSI) 结果. 这些发现表明,较低的Cap-Score结果不会对ICSI成功率产生负面影响.
科学领域:
- 生殖医学 生殖医学
- 安德罗学与人类学
- 不孕症治疗 不孕症治疗
背景情况:
- 降低精子容量能力与通过性交,IUI和常规试管婴儿的更低的受孕率有关.
- 精子功能受损的男性经常被转介进行细胞内质精子注射 (ICSI).
研究的目的:
- 评估通过Cap-Score评估的精子容量降低是否会影响ICSI结果.
- 为了确定Cap-Score对ICSI周期中受精,euploidy和怀孕率的影响.
主要方法:
- 在2018-2023年期间对199名接受ICSI的男性进行了回顾性分析.
- 低和正常Cap-Score组之间的受精率和euploidy率的比较.
- 后勤回归来评估Cap-Score对怀孕结果的独立预测值.
主要成果:
- 在低和正常的Cap-Score组之间,受精率和euploidy率相似 (分别为p=0.40和p=0.13).
- 在Cap-Score中,负和正妊娠指标 (hCG,临床妊娠,活产) 之间没有显著差异.
- 受精与女性年龄和检索的卵细胞有关;euploidy与女性年龄和精子运动有关.
结论:
- 在这个队列中,没有发现低Cap-Score和ICSI结果之间的关联.
- 低CAP分数的男性可以放心,他们的ICSI成功率与正常分数的男性相似.
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