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前列腺活检的演变:在局部麻醉下进行的跨膜和跨直肠方法的回顾性比较

Paul Lim¹, Amandeep Dosanjh¹, Meyada Ali¹

¹Urology, Worcestershire Acute Hospitals NHS Trust, Redditch, GBR.

|March 17, 2026

概括

在局部麻醉下进行的经膜活检 (LATP) 和经直肠超声活检 (TRUS) 显示前列腺癌检测的耐受性和并发症率相似. LATP显示了更高癌症检测率的趋势,表明其安全性和有效性.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
在瘤学瘤学.
医疗成像医学成像

背景情况:

第一线前列腺癌组织采样采用跨直肠超声活检 (TRUS) 或局部麻醉性跨膜活检 (LATP).
将这些技术进行比较对于优化患者的治疗结果和诊断准确度至关重要.

研究的目的:

为了比较LATP与前列腺癌TRUS的耐受性,并发症率和癌症检测率.
评估LATP作为一线前列腺活检方法的安全性和有效性.

主要方法:

一个回顾性,单中心的队列研究,涉及110名患者 (55名LATP,55名TRUS).
收集的数据包括患者人口统计数据,临床发现 (PSA,PI-RADS) 和通过电话问卷 (疼痛,并发症) 通过活检后的结果.
对这两种技术的癌症检测率都进行了分析.

主要成果:

无论是LATP还是TRUS,都表现出类似的程序耐受性和并发症概况 (例如,尿路困难,出血症).
在局部麻醉的经皮膜活检组显示了更高癌症检测率的趋势 (58.2%对47.3%),特别是在孤立的PI-RADS 4/5病例中.
两种方法之间没有观察到检测率或并发症的统计学上显著差异.

结论:

局部麻醉性透膜活检 (LATP) 是通过直肠超声活检 (TRUS) 进行初始前列腺癌诊断的安全有效替代方案.
LATP提供了可比的耐受性和并发症率,有可能改善癌症检测.

关键词:

癌症检测率癌症检测率并发症可能导致并发症.前列腺活检活检前列腺活检前列腺癌是前列腺癌.可以容忍的耐受性.通过经经.跨直肠的跨直肠的

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