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通过学术详细干预,在德克萨斯州社区药房增加布普伦诺芬和纳洛的获取
Sorina B Torrez1, Kirk E Evoy1, Kelly R Reveles1
1The University of Texas at Austin, TX, USA.
Substance use & addiction journal
|March 17, 2026
概括
邮寄的学术细节没有改善布普伦诺芬/纳洛储存或纳洛鼻喷雾的可用性. 然而,它适度增加了药店订购布普伦诺芬/纳洛的意愿,这表明了可扩展干预的潜力.
科学领域:
- 药理学和药房实践中的药理学和药房实践
- 公共卫生与成医学 公共卫生与成医学
背景情况:
- 治疗阿片类药物使用障碍 (OUD) 需要及时从药房获得布普伦诺芬/纳洛 (BUP/NX) 和纳洛鼻喷雾剂 (NNS).
- 现有的审计研究显示,药物可用性存在严重缺陷,阻碍了患者的获取.
- 干预措施对BUP/NX库存和非处方NNS可访问性的影响仍未得到充分研究.
研究的目的:
- 评估邮寄的学术详细干预措施对社区药房BUP/NX可用性的有效性.
- 评估干预对NNS无处方可访问性的影响.
- 为了确定药店准备库存或订购BUP/NX.的变化.
主要方法:
- 一项前性干预研究,涉及1000家德克萨斯州社区药房,随机分为干预或对照组.
- 干预组获得了关于BUP/NX和NNS的教育材料.
- 在干预之前和之后进行了电话秘密购物者审计,以评估库存,订购意愿和NNS可用性.
主要成果:
- 布普伦诺芬/纳洛储存率仍然很低,在任何一组的干预后都没有显著变化.
- 虽然干预组中订购BUP/NX的意愿显著增加,但整体库存和NNS可用性没有显示出显著的群体差异.
- 干预组显示,订购BUP/NX的可能性显著更高,并实现库存/订购意愿的复合结果.
结论:
- 邮寄的学术细节并没有显著改变BUP/NX库存或NNS可用性.
- 干预措施适度增加了药店订购BUP/NX的意愿,这表明潜在但有限的影响.
- 该干预措施是可扩展和可复制的,但需要修改以提高其在改善药物获取方面的有效性.
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