神经肌肉疾病中的性健康:一个范围审查揭示了被忽视的挑战
Audrey El Kaïm1, Marjorie Banos1, Valérie Decostre1
1Institute of Myology, Neuromuscular Investigation Center, Neuromuscular Physiology and Evaluation Laboratory, GH Pitié-Salpêtrière, Paris, France.
Journal of neuromuscular diseases
|March 17, 2026
概括
性功能障碍在患有神经肌肉疾病 (NMDs) 的成年人中是常见和复杂的. 存在研究缺口,特别是在女性方面,这凸显了综合性健康护理的需要.
科学领域:
- 神经学 神经学
- 性医学性医学性医学性医学
- 公共卫生 公共卫生
背景情况:
- 神经肌肉疾病 (NMDs) 导致渐进性残疾并影响整体生活质量.
- 性健康是幸福的关键方面,在NMD患者护理中经常被忽视.
- 本综述涉及未经研究的性功能障碍 (SD) 在患有NMD的成年人中.
研究的目的:
- 绘制和综合现有的有关NMD成年人性功能障碍的证据.
- 确定各种NMD中与SD相关的流行率,潜在机制和研究差距.
- 为临床实践和未来研究方向提供信息.
主要方法:
- 在PubMed,Cochrane图书馆和谷歌学者 (2025年2月至3月) 进行了系统的文献搜索.
- 包括报告成年人遗传或临床确认NMD的SD原始数据的研究.
- 数据根据PRISMA-ScR指南进行叙述合成,并使用引用跟踪.
主要成果:
- 分析了27项研究 (1983-2024年) 涉及2428个人.
- 性功能障碍在NMD中普遍存在,但异质,有各种原因,如阴性腺功能障碍,自主功能障碍和心理社会因素.
- 讨论的特定的NMD包括肌性缩症,夏科特-玛丽-牙病,粉样神经病变,炎症性肌病变,ALS,骨髓质疏松症和SMA.
结论:
- 性功能障碍是成年人患有NMD的常见,多因素和未被认可的问题.
- 目前的证据受到非包容性方法,稀缺的生理数据和了解女性性健康的差距的限制.
- 优先考虑将性健康评估纳入常规NMD护理是必不可少的.
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