癌症和验尸官之间的关系
JAMA
|February 21, 1977
概括
法医尸检在1.7%的病例中发现了癌症,提供了对未经治疗的疾病进展及其在突然死亡中的作用的见解. 这些发现对于病理学和医疗法律方面至关重要.
科学领域:
- 法医病理学 法医病理学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 在法医解剖中发现癌症的情况很少被报道.
- 法医尸检为未经治疗的癌症的自然历史提供了一个独特的窗口.
- 临床隐性癌症可以出乎意料或在解剖时出现.
研究的目的:
- 在法医解剖中确定癌症的发病率.
- 探索癌症在突然意外死亡中的作用.
- 突出法医解剖对了解癌症自然演变的价值.
主要方法:
- 对1300次连续的法医解剖进行审查.
- 癌症病例的识别和分类.
- 对癌症呈现和死亡原因的分析.
主要成果:
- 在各种主要部位和组织学类型的22例 (1.7%) 确诊癌症.
- 晚期癌症有时是突然,意想不到的死亡的原因.
- 已知癌症患者的自杀不常见,在明显的自杀病例中,尸检确认的癌症很少发生.
结论:
- 法医解剖对于识别癌症,包括神秘病例,是有价值的.
- 这些尸检为统计,临床和医疗法律目的提供了重要的数据.
- 法医病理学家通过这样的研究扮演着"社区病理学家"的重要角色.
相关概念视频
Cancer
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
What is Cancer?
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancer-Critical Genes II: Tumor Suppressor Genes
Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
What is Cancer?
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancer-Critical Genes II: Tumor Suppressor Genes
Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer Survival Analysis
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...


