在大量的和脂肪和不和脂肪饮食后,急性血小板变化
Lancet (London, England)
|April 24, 1976
概括
和脂肪 (S.F.) 是一种 缩短了凝血时间和降低了抗血素活性,而不和脂肪 (U.S.F.) 延长了凝血时间和增加了抗血素活性. 这两种脂肪类型都影响了血小板数量和体积.
科学领域:
- 营养科学 营养科学
- 血液学 血液学 血液学
- 心血管研究研究心血管研究
背景情况:
- 食脂肪显著影响生理过程.
- 了解不同类型的脂肪对血液静止的急性影响对于健康至关重要.
- 血小板激活和凝血通路是血液凝固的关键组成部分.
研究的目的:
- 调查和脂肪 (S.F.) 的直接影响. 和不和脂肪 (U.S.F.) 的使用. 关于血液凝固和血小板参数.
- 为了比较SF的不同影响. 与美国空军对抗. 在凝血因子和血小板行为上.
- 评估脂肪摄入后肝血栓凝固时间,抗血栓活性和血小板指数的变化.
主要方法:
- 健康的志愿者只吃了一顿富含SF的食物. 或美国空军.
- 血液样本分析了氨酸血栓凝固时间,这是血小板4因子释放的标志物.
- 在饭前和饭后测量了抗血素凝固活性和血小板计数/体积.
主要成果:
- 和脂肪 (S.F.) 是一种 缩短了氨酸血凝固时间和降低了抗血活性.
- 不和脂肪 (U.S.F.) 是一种不和脂肪. 延长了氨酸血凝固时间和增加了抗血活性.
- 这两者都是S.F. 和美国空军. 导致血小板数量的减少和血小板体积的增加.
结论:
- 在急性摄入中,S.F. 和美国空军. 不同地影响血液凝固参数.
- 这两种脂肪类型都会诱导血小板数量和体积的变化,这表明一般的前血栓倾向.
- 这些发现凸显了饮食脂肪成分的明显和直接的血静效应.
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