概括
维生素D缺乏导致亚洲儿童患上,已发现临床和亚临床病例. 需要立即采取行动,以解决这种在学龄儿童中广泛存在的公共卫生问题.
科学领域:
- 儿科 儿科 儿科
- 营养科学 营养科学
- 放射学 放射学是一门学科.
背景情况:
- 维生素D缺乏仍然是一个重大的全球健康问题.
- 风病是一种维生素D缺乏的表现,会影响儿童的骨发育.
- 某些种族群体对维生素D缺乏的倾向更高.
研究的目的:
- 评估亚洲,非洲,中国和苏格兰儿童中维生素D缺乏和恶心病的患病率.
- 关联维生素D缺乏的临床,生化和放射学发现.
- 为了评估血清25-基胆酸和酸酸酶水平的诊断效用.
主要方法:
- 临床检查以检查患有恶心病的人.
- 生物化学分析包括血清25-基胆酸和性酸酶.
- 放射性评估以检测患有病的迹象,包括表观细胞变化.
主要成果:
- 与非洲,中国和苏格兰儿童相比,亚洲儿童 (10名佛罗里达儿童,15名亚临床儿童) 患病的患病率明显高 (共7名亚临床儿童).
- 放射性征兆包括失去了形状细胞定义 (活跃的) 和形状细胞带 (愈合的).
- 低血清25-hydroxycholecalciferol水平被观察到在恶心,在"正常"范围的重叠;高性酸酶单独不是指示性的.
结论:
- 风,特别是亚临床形式,在亚洲儿童中非常普遍.
- 放射学发现对于诊断活跃和治愈病至关重要.
- 迫切需要公共卫生干预措施,以对抗危人群,特别是亚洲学龄儿童的维生素D缺乏症.
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