相关实验视频

Updated: Apr 26, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
16:24

Analyzing and Building Nucleic Acid Structures with 3DNA

Published on: April 26, 2013

20.3K

具有大肠杆菌染色体复制原点 (oriC) 和其他DNA位点的dnaA蛋白质复合体

R S Fuller, B E Funnell, A Kornberg

    Cell
    |October 1, 1984
    PubMed
    概括

    dnaA蛋白与特定的DNA序列结合,包括大肠杆菌复制起源 (oriC),以启动DNA复制. 这种蛋白质在这些部位形成大型复合体,对细菌DNA复制至关重要.

    更多相关视频

    Determination of the Optimal Chromosomal Locations for a DNA Element in Escherichia coli Using a Novel Transposon-mediated Approach11:12

    Determination of the Optimal Chromosomal Locations for a DNA Element in Escherichia coli Using a Novel Transposon-mediated Approach

    Published on: September 11, 2017

    6.8K
    Visualizing the Interaction Between the Qdot-labeled Protein and Site-specifically Modified λ DNA at the Single Molecule Level08:56

    Visualizing the Interaction Between the Qdot-labeled Protein and Site-specifically Modified λ DNA at the Single Molecule Level

    Published on: July 17, 2018

    6.5K

    相关概念视频

    Replication in Prokaryotes02:35

    Replication in Prokaryotes

    Overview
    86.4K
    Replication in Eukaryotes02:31

    Replication in Eukaryotes

    Overview
    156.8K
    The DNA Replication Fork01:02

    The DNA Replication Fork

    An organism’s genome needs to be duplicated in an efficient and error-free manner for its growth and survival. The replication fork is a Y-shaped active region where two strands of DNA are separated and replicated continuously. The coupling of DNA unzipping and complementary strand synthesis is a characteristic feature of a replication fork.   Organisms with small circular DNA, such as E. coli, often have a single origin of replication; therefore, they have only two replication...
    30.5K
    Replication in Prokaryotes01:32

    Replication in Prokaryotes

    DNA replication has three main steps: initiation, elongation, and termination. Replication in prokaryotes begins when initiator proteins bind to the single origin of replication (ori) on the cell's circular chromosome. Replication then proceeds around the entire circle of the chromosome in each direction from the two replication forks, resulting in two DNA molecules.
    Many Proteins Work Together to Replicate the Chromosome
    Replication is coordinated and carried out by a host of specialized...
    20.3K
    Replication in Eukaryotes01:29

    Replication in Eukaryotes

    In eukaryotic cells, DNA replication is highly conserved and tightly regulated. Multiple linear chromosomes must be duplicated with high fidelity before cell division, so there are many proteins that fulfill specialized roles in the replication process. Replication occurs in three phases: initiation, elongation, and termination, and ends with two complete sets of chromosomes in the nucleus.
    Many Proteins Orchestrate Replication at the Origin
    Eukaryotic replication follows many of the same...
    15.2K
    Nucleoid01:24

    Nucleoid

    The nucleoid represents a structurally and functionally distinct region within prokaryotic cells, where the cell's DNA and associated proteins are housed. Unlike eukaryotic cells, prokaryotes lack a membrane-bound nucleus, and the nucleoid facilitates the organization and accessibility of the genetic material within this constraint. The DNA in most bacteria and archaea exists as a single, circular, double-stranded molecule that is highly compacted through supercoiling and interactions with...
    2.2K