在囊性纤维化患者之间是否会发生假名菌的交叉感染?
Lancet (London, England)
|September 25, 1982
概括
在囊性纤维化 (CF) 患者中,环境暴露是 Pseudomonas aeruginosa 菌株的主要来源. 在CF患者之间显著的交叉感染需要长期的,密切的接触.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- Pseudomonas aeruginosa 是囊性纤维化 (CF) 患者中一个重要的机会性病原体.
- 了解P. aeruginosa的传播动态对于CF护理中的感染控制至关重要.
研究的目的:
- 调查囊性纤维化患者中P. aeruginosa呼吸道感染的来源和传播模式.
- 确定患者接触与环境获取在P. aeruginosa殖民中的作用.
主要方法:
- 在12个月内从CF患者中分离P. aeruginosa的细菌类型.
- 利用血清学和皮奥辛生产来进行菌株分化.
- 与患者接触水平和家庭关系相关联的菌株数据.
主要成果:
- 在四名无关患者中确定了一种P. aeruginosa菌株,这表明环境收购.
- 六对兄弟姐妹共享相同的菌株,但兄弟姐妹之间的菌株是不同的.
- 在非接触患者中没有发现广泛的交叉感染的证据.
结论:
- 环境似乎是P. aeruginosa菌株殖民CF患者的主要来源.
- 囊性纤维化患者之间的交叉感染需要长期和亲密的接触.
- 环境监测和控制措施对于在CF环境中管理P. aeruginosa可能至关重要.
相关概念视频
Transmission-based Precautions II: Airborne and Protective Environment
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Cystic Fibrosis: Pathogenesis
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...
Cystic Fibrosis: Management
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic sinusitis...
Sinus disease and chronic sinusitis...
Pneumonia I: Introduction
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Atypical Pneumonia
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pneumonia I: Introduction
Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...


