在连续的门诊腹膜透析中的腹膜炎. 实验室和临床研究研究
Lancet (London, England)
|December 18, 1982
概括
持续的门诊腹膜透析 (CAPD) 显著降低了腹膜炎的发生率,其中83%的病例得到了成功的抗生素治疗. 然而,腹膜炎仍然是一个主要的并发症,需要为CAPD提供足够的设施.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 内部医学 内部医学
背景情况:
- 持续的门诊腹膜透析 (CAPD) 是对末期脏疾病的治疗方法.
- 腹膜炎是与CAPD相关的重大并发症,影响患者的治疗结果.
- 抗生素治疗是CAPD相关的腹膜炎的主要治疗方法.
研究的目的:
- 在三年内评估CAPD患者腹膜炎的发病率和治疗结果.
- 评估抗生素治疗的有效性,特别是腹腔内塞福洛キシ姆,用于管理CAPD腹腔炎.
- 分析腹膜炎对CAPD失败率和住院病人的影响.
主要方法:
- 在1979年至1981年间对82名接受CAPD治疗的患者进行了回顾性分析.
- 追踪腹膜炎发作,治疗策略和患者的治疗结果.
- 监测并发症,如Clostridium难性结肠炎和抗生素政策的变化.
主要成果:
- 周周炎的发病率从每20个患者周的1次发病减少到每37个患者周的1次发病.
- 在136例腹膜炎发作中,有83%成功地用抗生素治疗;62%用腹膜内塞福洛キシ姆治疗.
- 16%的患者因腹膜炎而经历了CAPD失败;住院平均为4.3天/患者/年.
结论:
- 在CAPD中腹膜炎的发病率可以显著降低.
- 肠内素是CAPD周周炎的有效治疗方法,尽管整体周周炎仍然是一个挑战.
- 适当的设施和修订的抗生素政策 (例如,网胺和胺) 对于最大限度地减少CAPD中腹膜炎并发症至关重要.
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