患有脑疟疾的患者是否有脑? 一个计算机断层扫描研究研究
Lancet (London, England)
|February 26, 1983
概括
在严重脑疟疾患者的计算机断层扫描显示,只有两例致命病例的脑. 正常的扫描是常见的,表明大脑胀并不总是这些患者昏迷的原因.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
背景情况:
- 严重的大脑疟疾是Plasmodium falciparum感染的危及生命的并发症.
- 脑性疟疾的神经表现,包括昏迷,尚未完全理解.
- 脑在脑疟疾病理生理学中的作用需要进一步调查.
研究的目的:
- 用计算机断层扫描 (CT) 来调查严重脑疟疾患者脑的存在和重要性.
- 确定CT发现是否与临床结果相关,包括死亡率和神经学缺陷.
主要方法:
- 对10名被诊断患有严重脑疟疾的患者进行了脑部计算机断层扫描 (CT).
- 收集了所有患者的临床数据,包括神经状态和结果 (生存或死亡).
- 在康复期间,在一些幸存的患者中进行了随访CT扫描.
主要成果:
- 在5例致命病例中,只有2例中检测到脑.
- 在4名患者中观察到细微的密度变化区域,与焦点神经症状无关.
- 这些变化的密度在2名幸存者的随访扫描中持续存在.
- 四名患者,包括一名死亡者,CT扫描完全正常.
- 在患有严重脑性疟疾的患者中,脑并未始终被观察到,即使在致命的情况下也是如此.
结论:
- 大脑可能存在于严重的大脑疟疾中,但并不是一个普遍的发现.
- 在CT扫描中没有一致的脑,这表明其他病理生理机制可能会导致严重脑疟疾的昏迷.
- 在患有严重脑性疟疾的患者中,CT成像可能并不总是揭示昏迷的原因.
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