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Published on: November 25, 2010

在细胞培养中选择快速生长的Sindbis病毒突变在动物中显示衰弱的毒性

R A Olmsted, R S Baric, B A Sawyer

    Science (New York, N.Y.)
    |July 27, 1984
    PubMed
    概括

    辛迪斯病毒突变在细胞培养中生长得更快,在小鼠中变得不那么致命. 这表明快速的细胞生长和改变的病毒结构可能导致有效的减弱疫苗.

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    Viral Recombination

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