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Updated: May 13, 2026

Retroviral Transduction of Bone Marrow Progenitor Cells to Generate T-cell Receptor Retrogenic Mice
09:08

Retroviral Transduction of Bone Marrow Progenitor Cells to Generate T-cell Receptor Retrogenic Mice

Published on: July 11, 2016

基因转换和多态化:通过玛2b链基因转换通过差异基因转换生成小鼠免疫球蛋白玛2a链等位基因

R Ollo, F Rougeon

    Cell
    |February 1, 1983
    PubMed
    概括

    小鼠免疫球蛋白基因等位基因在C57BL/6和BALB/c菌株之间显示出显著的差异. 基因转换可能驱动免疫球蛋白玛基因中的这种分歧和多态性.

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    Published on: February 6, 2018

    Characterization of Thymus-dependent and Thymus-independent Immunoglobulin Isotype Responses in Mice Using Enzyme-linked Immunosorbent Assay06:15

    Characterization of Thymus-dependent and Thymus-independent Immunoglobulin Isotype Responses in Mice Using Enzyme-linked Immunosorbent Assay

    Published on: September 7, 2018

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    Gene Conversion02:08

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    Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...