在小鼠15号染色体上假定乳腺瘤基因 (int-1) 的前病毒激活方式

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Updated: Jul 30, 2026

Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer
07:13

Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer

Published on: March 26, 2014

R Nusse, A van Ooyen, D Cox

    Nature
    |January 12, 1984
    PubMed
    概括

    小鼠乳腺瘤病毒 (MMTV) 通过在int-1基因附近的前病毒插入,诱导小鼠乳腺癌. 这种插入激活了int-1基因,一个潜在的瘤基因,在瘤中,但不是正常组织.

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